Publications (Selected from recent 5 years)
- So DHF, Chan JCY, Tsui MG, Tsang PSW , Yao KM* (2020) Secreted PDZD2 exerts an insulinotropic effect on INS-1E cells by a PKA-dependent mechanism. Molecular and Cellular Endocrinology 518: 111026
- Sarwar MS, Xia YX, Liang ZM, Tsang SW , Zhang HJ* (2020) Mechanistic pathways and molecular targets of plant-derived anticancer ent -kaurane diterpenes. Biomolecules 10(1): pii: E144
- Xia Y, Lam CS, Li W, Sarwar MS, Liu K, Lee KM, Zhang HJ*, Tsang SW * (2019) Flexicaulin A, an ent -kaurane diterpenoid, activates p21 and inhibits the proliferation of colorectal carcinoma cells through a non-apoptotic mechanism. International Journal of Molecular Sciences 20(8): pii: E1917
- Xu XY # , Tsang SW # , Guan YF # , Liu KL, Pan WH, Lam CS, Lee KM, Xia YX, Xie WJ, Wong WY, Lee MML, Tai WCS, Zhang HJ* (2019) In vitro and in vivo antitumor effects of plant-derived miliusanes and their induction of cellular senescence. Journal of Medicinal Chemistry 62(3): 1541-1561
- Wong HLX # , Qin HY # , Tsang SW , Zuo X, Che S, Chow CFW, Li X, Xiao HT, Zhao L, Huang T, Lin CY, Kwan HY, Yang T, Longo FM, Lyu A, Bian ZX* (2019) Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling. Nature Communications 10(1): 1745
- Xia Y # , Xiao HT # , Liu KL, Zhang HJ*, Tsang SW * (2018) Resveratrol ameliorates the severity of fibrogenesis in mice with experimental chronic pancreatitis. Molecular Nutrition and Food Research 62(16): e1700561
- Zhu Y # , Pan WH # , Ku CF, Zhang HJ*, Tsang SW * (2018) Design, synthesis and evaluation of novel dihydrostilbene derivatives as potential anti-melanogenic skin-protecting agents. European Journal of Medicinal Chemistry 143: 1254-1260
- Sarwar MS, Zhang HJ, Tsang SW * (2018) Perspectives of plant natural products in inhibition of cancer invasion and metastasis by regulating multiple signaling pathways. Current Medicinal Chemistry 25(38): 5057-5087
- Guo L # , Tsang SW # , Zhang TX, Liu KL, Guan YF, Wang B, Sun HD, Zhang HJ*, Wong MS* (2017) Efficient semisynthesis of (−)-pseudoirroratin A from (−)-flexicaulin A and assessment of their antitumor activities. ACS Medicinal Chemistry Letters 8(3): 372-376.
Patents (Selected from recent 5 years)
- US10493056B2 (12/2019) Method of use of diterpenoid derivatives as anticancer agents – CIP
- US10351500B2 (07/2019) Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants as antimicrobial agents
- US10188590B2 (01/2019) Skin-protection composition containing Dendrobium-based ingredients – CIP
- US10017442B2 (07/2018) Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatment of tumorous pathologies
- US9956152B2 (05/2018) Skin-protection composition containing Dendrobium-based ingredients HK1206618 (05/2018) 一种用于治疗炎症性肠病的中草药配方及其制备方法
- CN201410210304.0 (04/2018) 黄烷醇糖苷在抑制星状细胞活化上的应用
- US9877931B2 (01/2018) Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions – CIP
